Search results for "activity [Sun]"

showing 10 items of 36 documents

Cross inhibition improves activity selection when switching incurs time costs

2015

Abstract We consider a behavioural model of an animal choosing between two activities, based on positive feedback, and examine the effect of introducing cross inhibition between the motivations for the two activities. While cross-inhibition has previously been included in models of decision making, the question of what benefit it may provide to an animal’s activity selection behaviour has not previously been studied. In neuroscience and in collective behaviour cross-inhibition, and other equivalent means of coupling evidence-accumulating pathways, have been shown to approximate statistically-optimal decision-making and to adaptively break deadlock, thereby improving decision performance. Sw…

0106 biological sciencesCross inhibitionMathematical optimizationComputer science[SDV]Life Sciences [q-bio]010603 evolutionary biology01 natural sciencesTime cost0501 psychology and cognitive sciencesForaging050102 behavioral science & comparative psychologyGeometric frameworkkäyttäytyminenSelection (genetic algorithm)Positive feedbackBehaviorGeometric Framework05 social sciencesActivity selectionDeadlock (game theory)Cross inhibitionActivity SelectionGeometric frameworkCoupling (computer programming)Cross InhibitionAnimal Science and ZoologyDecision processNeuroscienceCurrent Zoology
researchProduct

English Language Policy in Relation to Teachers and Teacher Educators in Latvia: Insights from Activity Systems Analysis

2020

The ambitious objectives of European language policy and the strive for competitiveness have led to an increasing emphasis on foreign language competence at the level of national education systems. Using Spolsky’s onion model of language policy (2004) and Engeström’s Expansive Learning theory (1987, 2008), the study attempts to determine the formative influence of the existing multilayered language policy on the professional development of Latvian educators with the aim to compare the situation for teachers and teacher educators in respect of their English language proficiency.Given the prioritisation of English and strategic differences in foreign language management in relation to teacher…

0209 industrial biotechnologyacademic staffForeign language02 engineering and technologyOnion modellcsh:Education (General)EducationFormative assessmentactivity systems analysis020901 industrial engineering & automationPedagogyAgency (sociology)SociologyCompetence (human resources)Language policyteachers05 social sciencesProfessional development050301 educationLatvianlanguage.human_languagelanguage policydevelopment of English language proficiencylanguagelcsh:L7-9910503 educationActa Paedagogica Vilnensia
researchProduct

Cellular complexity in MAPK signaling in plants: Questions and emerging tools to answer them

2018

International audience; Mitogen activated protein kinase (MAPK) cascades play an important role in many aspects of plant growth, development, and environmental response. Because of their central role in many important processes, MAPKs have been extensively studied using biochemical and genetic approaches. This work has allowed for the identification of the MAPK genes and proteins involved in a number of different signaling pathways. Less well developed, however, is our understanding of how MAPK cascades and their corresponding signaling pathways are organized at subcellular levels. In this review, we will provide an overview of plant MAPK signaling, including a discussion of what is known a…

0301 basic medicineMAPK/ERK pathwayactivity sensorsPlant growth[SDV]Life Sciences [q-bio]plantComputational biologyPlant ScienceReviewlcsh:Plant culture03 medical and health sciences[SDV.BV]Life Sciences [q-bio]/Vegetal Biologylcsh:SB1-1110biologyphosphorylationsignaling cascade;MAPK;phosphorylation;plant;microscopy;activity sensorsSubcellular localizationMAPKMapk signaling030104 developmental biologyMitogen-activated protein kinasebiology.proteinmicroscopyPhosphorylationSignal transductionExperimental methodssignaling cascade
researchProduct

Metabolic signatures across the full spectrum of non-alcoholic fatty liver disease.

2022

Funder: European Commission

ALTtype 2 diabetes mellitusROC receiving operator characteristicaspartate aminotransferaseHSDLDL low-density lipoproteinUHPLC ultrahigh-performance liquid chromatographyROCHCCNon-alcoholic steatohepatitisGCPCANASHGastroenterology2-HB 2-hydroxybutanoic acid; 3-HB 3-hydroxybutanoic acid; ALT alanine aminotransferase; AST aspartate aminotransferase; CE cholesterol ester; Cer ceramide; FFA free fatty acid; FLIP Fatty Liver Inhibition of Progression; Fibrosis; GC gas chromatography; HCC hepatocellular carcinoma; HSD honest significant difference; LC lipid cluster; LDL low-density lipoprotein; LM lipid and metabolite; LMC lipid metabolite and clinical variable; LPC lysophosphatidylcholine; Lipidomics; Mass spectrometry; Metabolomics; NAFL non-alcoholic fatty liver; NAFLD non-alcoholic fatty liver disease; NAS NASH activity score; NASH non-alcoholic steatohepatitis; NIDDK NASH-CRN National Institute of Digestive Diseases and Kidney NASH Clinical Research Network; NRR non-rejection rate; Non-alcoholic steatohepatitis; PC(O) ether PC; PC phosphatidylcholine; PCA principal component analysis; PE phosphatidylethanolamine; QTOFMS quadrupole-time-of-flight mass spectrometry; ROC receiving operator characteristic; SAF steatosis activity and fibrosis; SM sphingomyelin; T2DM type 2 diabetes mellitus; TG triacylglycerol; UHPLC ultrahigh-performance liquid chromatographySAFSAF steatosis activity and fibrosisLM lipid and metabolitehonest significant differenceHSD honest significant differenceTG triacylglycerolnon-rejection ratecholesterol esterPCPEGC gas chromatographyfree fatty acidFLIPNASH non-alcoholic steatohepatitisNIDDK NASH-CRN National Institute of Digestive Diseases and Kidney NASH Clinical Research NetworkBIOMARKERST2DMPE phosphatidylethanolamineLDLlipidNAFLDFFA free fatty acid2-HBMetabolomicsNAFL non-alcoholic fatty liverLMCphosphatidylcholineScience & TechnologySM sphingomyelinGastroenterology & HepatologyMass spectrometryactivitynutritional and metabolic diseasesT2DM type 2 diabetes mellitusACIDSreceiving operator characteristicdigestive system diseasesquadrupole-time-of-flight mass spectrometryLC lipid clusterlow-density lipoproteinNAS2-HB 2-hydroxybutanoic acidNAS NASH activity scoreQTOFMSether PCNRRSCORING SYSTEMprincipal component analysisgas chromatographyLC2-hydroxybutanoic acidPROGRESSIONAST aspartate aminotransferaseLMPC phosphatidylcholinePC(O)MARKERSUHPLCsteatosisTOOLImmunology and AllergyINSULIN-RESISTANCECerSMFatty Liver Inhibition of Progressionhepatocellular carcinoma2-HB 2-hydroxybutanoic acid NIDDK NASH-CRN National Institute of Digestive Diseases and Kidney NASH Clinical Research Network NRR non-rejection rate Non-alcoholic steatohepatitis PC(O) ether PC PC phosphatidylcholine PCA principal component analysis PE phosphatidylethanolamine QTOFMS quadrupole-time-of-flight mass spectrometry ROC receiving operator characteristic SAF steatosis activity and fibrosis SM T2DM type 2 diabetes mellitus TG triacylglycerol UHPLC ultrahigh-performance liquid chromatographyultrahigh-performance liquid chromatographyCELPC3-HBNAFLnon-alcoholic fatty liverTGtriacylglycerolNRR non-rejection rateLife Sciences & BiomedicineNAFLD non-alcoholic fatty liver diseaseFLIP Fatty Liver Inhibition of Progressionalanine aminotransferasemetaboliteCer ceramideCE cholesterol estersphingomyelinlysophosphatidylcholineand fibrosisALT alanine aminotransferaseInternal MedicineceramideNational Institute of Digestive Diseases and Kidney NASH Clinical Research NetworkAST3-HB 3-hydroxybutanoic acidQTOFMS quadrupole-time-of-flight mass spectrometryPCA principal component analysisLPC lysophosphatidylcholineHepatologynon-alcoholic fatty liver diseaseand clinical variablePC(O) ether PC3-hydroxybutanoic acidFibrosisNASH activity scoreNIDDK NASH-CRNlipid clusterlipid and metabolitephosphatidylethanolamineLipidomicsLMC lipid metabolite and clinical variableFFAHCC hepatocellular carcinomaJHEP reports : innovation in hepatology
researchProduct

Utility and appropriateness of the fatty liver inhibition of progression (FLIP) algorithm and steatosis, activity, and fibrosis (SAF) score in the ev…

2013

Biopsy is still the gold standard for the diagnosis of nonalcoholic steatohepatitis but the definition may vary among pathologists, a drawback especially in evaluation of biopsies for clinical trials. We previously developed a scoring system (steatosis, activity, fibrosis [SAF]) allowing the use of an algorithm (fatty liver inhibition of progression [FLIP]) for the classification of liver injury in morbid obesity. The aim of this study was to determine whether the use of the SAF score and FLIP algorithm can decrease interobserver variations among pathologists. In a first session, pathologists categorized 40 liver biopsies of patients with nonalcoholic fatty liver disease (NAFLD) according t…

AdultLiver CirrhosisMalemedicine.medical_specialtyConcordanceBiopsySettore MED/08 - Anatomia PatologicaSeverity of Illness IndexFibrosisNon-alcoholic Fatty Liver DiseaseInternal medicineSAF steatosis activity fibrosis.Nonalcoholic fatty liver diseaseBiopsyNAS nonalcoholic steatohepatitis activity scoremedicineHumansAgedObserver VariationHepatologymedicine.diagnostic_testbusiness.industryFatty liverGold standard (test)HepatologyMiddle Agedmedicine.diseaseFatty LiverLiverNASH nonalcoholic steatohepatitiDisease ProgressionFemaleNAFLD nonalcoholic fatty liver diseaseSteatosisbusinessAlgorithmAlgorithmsHepatology (Baltimore, Md.)
researchProduct

Multiple lifestyle factors and depressed mood: a cross-sectional and longitudinal analysis of the UK Biobank (N = 84,860)

2020

Abstract Background There is now evolving data exploring the relationship between depression and various individual lifestyle factors such as diet, physical activity, sleep, alcohol intake, and tobacco smoking. While this data is compelling, there is a paucity of longitudinal research examining how multiple lifestyle factors relate to depressed mood, and how these relations may differ in individuals with major depressive disorder (MDD) and those without a depressive disorder, as ‘healthy controls’ (HC). Methods To this end, we assessed the relationships between 6 key lifestyle factors (measured via self-report) and depressed mood (measured via a relevant item from the Patient Health Questio…

AdultMalemedicine.medical_specialtyAdolescentExacerbationlcsh:Medicinebehavioral disciplines and activitiesYoung Adult03 medical and health sciencesScreen time0302 clinical medicineInternal medicinemental disordersmedicineLifestyle medicineHumansLife StyleLifestyle medicineDepression (differential diagnoses)Biological Specimen BanksDepressive Disorder MajorPhysical activitybusiness.industrylcsh:RGeneral Medicinemedicine.diseaseMental healthUnited KingdomScreen timeDiet030227 psychiatryPatient Health QuestionnaireCross-Sectional StudiesDiet Health Lifestyle medicine Mood disorders Physical activity Screen time Adolescent Adult Biological Specimen Banks Cross-Sectional Studies Depressive Disorder Major Female Humans Male United Kingdom Young Adult Life StyleMood disordersHealthMood disordersMajor depressive disorderFemalebusiness030217 neurology & neurosurgeryResearch Article
researchProduct

Use of Biologics to Treat Relapsing and/or Refractory Eosinophilic Granulomatosis With Polyangiitis: Data From a European Collaborative Study.

2021

OBJECTIVE To describe the efficacy and safety of biologics for the treatment of eosinophilic granulomatosis with polyangiitis (EGPA). METHODS A retrospective European collaborative study was conducted in patients with EGPA who received treatment with biologics for refractory and/or relapsing disease. RESULTS Among the 147 patients with EGPA included in the study, 63 received rituximab (RTX), 51 received mepolizumab (MEPO), and 33 received omalizumab (OMA). At the time of inclusion, the median Birmingham Vasculitis Activity Score (BVAS) was 8.5 (interquartile range [IQR] 5-13) in the RTX group, while the median BVAS in the OMA group was 2 (IQR 1-4.5) and the median BVAS in the MEPO group was…

AdultMalemedicine.medical_specialtyImmunologyBirmingham Vasculitis Activity ScoreOmalizumabOmalizumabChurg-Strauss SyndromeAntibodies Monoclonal Humanized03 medical and health sciences0302 clinical medicineRheumatologyInterquartile rangeRecurrenceInternal medicinemedicineImmunology and AllergyHumansImmunologic Factors030212 general & internal medicineTreatment FailureAdverse effectGlucocorticoidsAgedRetrospective Studies030203 arthritis & rheumatologyBiological Productsbusiness.industryMiddle Agedmedicine.diseaseAsthmaTreatment OutcomeRituximabFemaleVasculitisbusinessGranulomatosis with polyangiitisRituximabMepolizumabmedicine.drugArthritisrheumatology (Hoboken, N.J.)References
researchProduct

Assessing behavioural problems and assets in children and adolescents

1990

Abstract The main purpose of this brief report is to introduce a wide range battery of instruments for the psychological assessment of children and adolescents, which was developed in Spain and coordinated by the last author. The battery includes a General Diagnostic Report (anamnesis and general way of life), two Behaviour Problem Scales (one for school and one for non-school settings), a Hyperactivity Scale, the ‘Battery of Socialization’, the I-6 (Junior) Questionnaire, the EPQ-J, a Questionnaire for the Assessment of Self-Concept, the Antisocial Behaviour Scale, a Locus of Control Scale, an Irrational Beliefs Inventory, an Assertiveness Scale, a Fear Inventory, an Anxiety Scale, a Depre…

AnamnesisLocus of controlScale (ratio)Hyperactivity Scalemedia_common.quotation_subjectSocializationPersonalityAssertivenessPsychological testingPsychologyGeneral Psychologymedia_commonDevelopmental psychologyPersonality and Individual Differences
researchProduct

La inserción laboral de los inmigrantes rumanos y búlgaros en España

2008

Este artículo analiza la incorporación al mercado de trabajo español de los inmigrantes de nacionalidad búlgara y rumana, dos de los colectivos extranjeros que más han crecido en los últimos años. Tras elaborar un breve estado de la cuestión sobre el tema, se analiza su evolución numérica reciente y su distribución geogràfica a nivel de Comunidades Autónomas, sus características sociodemográficas y laborales a partir de la EPA y, finalmente, su inserción laboral por sector de actividad desde la perspectiva de la complementariedad con la población española ocupada en esos mismos sectores. Las conclusiones se centran en subrayar tanto las semejanzas como las diferencias existentes entre ambos…

Análisis sectorialGeografíaUNESCO::HISTORIARomaniaEspañaRumaníaGeociencias. Medio ambienteDistribución geográficaInmigración extranjeraLabour marketGeographic DistributionActivity sector analysisSpainGrupo BForeign immigration:HISTORIA [UNESCO]Mercado de TrabajoBulgaria
researchProduct

The Relationship Between Sleep Characteristics and Unmet Physical Activity Need in Older Women

2018

Objective: We examined among older women the association of sleep quality, daytime tiredness, and sleep duration with unmet physical activity need, that is, wishing to be more physically active but perceiving no opportunity for it. Method: Cross-sectional logistic regression analyses among women aged 74 to 86 years (Finnish Twin Study on Aging, third wave, n = 302). Results: Thirty-one participants reported unmet physical activity need. Short sleepers had fivefold and long sleepers threefold odds for unmet physical activity need compared with normative sleepers, while for daytime tiredness the odds were double. Presence of daytime tiredness and unmet physical activity coincided with higher…

GerontologyPREDICTORTime FactorsväsymysLogistic regressiondaytime tirednessFATIGUECohort Studies0302 clinical medicineOBJECTIVE SLEEPMedicine030212 general & internal medicineFinlandAged 80 and oversleep qualityuni (biologiset ilmiöt)Sleep in non-human animalsHEALTH-BENEFITSDEPRESSIVE SYMPTOMSFemale0305 other medical sciencefyysinen aktiivisuusSleep durationBASIC NEEDSDURATIONPhysical activityDisorders of Excessive SomnolenceOdds03 medical and health sciencesQUALITYHumansExerciseDepressive symptomsunihäiriötAgedCommunity and Home Care030505 public healthSleep qualitybusiness.industryMORTALITYagingADULTSTwin study3141 Health care scienceCross-Sectional Studiesikääntyminen3121 General medicine internal medicine and other clinical medicineunmet physical activity needsleep durationGeriatrics and GerontologybusinessSleepGerontology
researchProduct